Quality management in Biobanking

Biomedical investigators require high quality human tissue to support their research; thus, an important aspect of the provision of tissues by biorepositories is the assurance of high quality and consistency of processing specimens. This is best accomplished by a quality management system (QMS). The basis of a QMS program designed to aid biorepositories that want to improve their operations. In 1983, the UAB Tissue Collection and Biobanking Facility (TCBF) introduced a QMS program focused on providing solid tissues to support a wide range of research; this QMS included a quality control examination of the specific specimens provided for research. Similarly, the Division of Laboratory Sciences at the Centers for Disease Control and Prevention (CDC) introduced a QMS program for their laboratory analyses, focused primarily on bodily fluids. The authors of this article bring together the experience of the QMS programs at these two sites to facilitate the development or improvement of quality management systems of a wide range of biorepositories.

  • Impact of Biobanking and Clinical Databases
  • Dried Blood Spots: New Applications for Biobanking?
  • Tissue Screening, Preparation and Antibiotic Sterilization
  • Role of QMS in improving of biobank standards
  • Sample integrity and quality assured biobanking
  • Accreditation and Certification of Biobanks
  • Forensic Study of Identity
  • QMS implementation in maintenance and sustainability of biobanks

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